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Microfluidic Chips for Sperm Selection

What is it?

The FERTILE® chip is a simple and innovative sperm selection device.

Through the microfluidic technique, it selects sperm with the most intact genetic material, that is, with less DNA fragmentation, to subsequently use them in an IVF-ICSI cycle.

This technique mimics the conditions of the female vaginal tract, which is a formidable selector in terms of the number and integrity of sperm that reach the oocyte.

Sperm selected with FERTILE® show better motility, morphology, low DNA fragmentation rates, and lower amounts of reactive oxygen species (ROS) compared to other traditional methods.

Who is it indicated for?

It is used in cases where the semen sample presents high sperm DNA fragmentation.

What is sperm DNA fragmentation?

These are breaks or lesions in the genetic material of the spermatozoon. A high level of this fragmentation can cause male infertility and compromise the possibility of achieving a natural pregnancy.

A sperm DNA fragmentation study is recommended in the following situations:

  • Absence of pregnancy.
  • Idiopathic infertility.
  • Recurrent miscarriages.
  • Implantation failures.
  • Low embryo quality and low rate of embryos reaching the blastocyst stage.

It is important to remember that improving diagnosis and applying specific treatments can help enhance the chances of success in assisted reproduction treatments.